The Gold Certification means that Xerox achieves leading benchmark levels in all aspects of ethical, sustainable and strategic procurement when measured against CIPS globally respected standards which are structured around leadership and organization, strategy, people, process and systems, and performance measurement and management. It is also the oldest non-military technical university in Europe. The project codename was Prfstand XII ("Test stand XII"), sometimes called the rocket U-boat. Xerox received the second highest placement on the "Ability to deliver immediate benefit" axis. The United Kingdom of Great Britain and Northern Ireland, commonly known as the United Kingdom (UK) or Britain, is a country in Europe, off the north-western coast of the continental mainland. It is possible that some nucleic acid species could serve as negative or positive markers of some EVs. The original German designation of the rocket was "V2",[7][41] unhyphenated exactly as used for any Third Reich-era "second prototype" example of an RLM-registered German aircraft design but U.S. publications such as Life magazine were using the hyphenated form "V-2" as early as December 1944.[42]. Watts and Strogatz showed that, beginning with a regular lattice, the addition of a small number of random links reduces the diameterthe longest direct path between any two vertices in the networkfrom being very long to being very short. Quantification of total lipids can be achieved, e.g. Proteins presumably actively incorporated into EVs are those with ability to bind to membranes or to cytosolic sequences of transmembrane proteins. The study focused on imaging equipment providers net-zero strategies, commitments, and sustainability services and solutions that enable innovation and growth while helping customers reduce their environmental impact. This publication is recognized as one of the most respected source of employment and career information for Hispanic women in the country. Culture and harvesting conditions such as passage number (or days in culture for suspension cells), seeding density [14], density/confluence at harvest [14], including any relevant post-confluence characteristics such as development of polarity [1519] (in that case, were EVs collected globally or separately, from the different parts of polarized cells? Given the wide range of techniques and platforms available, many of which remain under development for EV applications, MISEV2018 cannot yet give precise protocol recommendations. In attendance were Speer, Air Marshal Erhard Milch, Admiral Karl Dnitz, Col. General Friedrich Fromm, and Karl Saur. Possibly, ongoing development of fluorescence capabilities of NTA devices may ultimately allow EV-specific measurement [181], although assay sensitivity and the tendency of labeling antibodies and lipid dyes to form particles pose substantial hurdles to such applications [127,182]. Table 2 summarizes the instructions given in MISEV2014 for EV characterization, and their updates in MISEV2018. The group was gradually captured by the Gestapo and most of the members were executed. [12], The small-world question is still a popular research topic today, with many experiments still being conducted. 20 on 2020 listing. A growing number of separation techniques and combinations thereof are available, variously balancing recovery and specificity. In the categories of corporate code of conduct, corporate governance and environmental management and reporting, Xerox exceeded the average score of DJSI World Members. FORTUNE magazine's annual ranking of the World's Most Admired Companies places Xerox at the No. See news release. The judging panel consisted of renowned experts from companies such as LNS Research, Anheiser-Busch InBev, GlaxoSmithKline, ConAgra Foods, Owen-Corning and others, as well as some well-known industry consultants. Single and multiple measures and implications for purity. Were isolated EVs analyzed or used for experiments fresh, frozen/thawed, lyophilized and reconstituted, etc.? This observation, in turn, was loosely based on the seminal demographic work of the Statists who were so influential in the design of Eastern European cities during that period. that EVs may contribute, but not necessarily exclusively, to an observed phenomenon or molecular signature. Shortly after the experiments began, letters would begin arriving to the targets and the researchers would receive postcards from the respondents. dBoth size exclusion chromatography (SEC) and density gradients may co-isolate EVs and certain lipoproteins. The small-world experiment comprised several experiments conducted by Stanley Milgram and other researchers examining the average path length for social networks of people in the United States. Xerox was named to the Hall of Fame after achieving five consecutive years of certification in the J.D. The award recognizes the excellent work submitted by an agency or organization. Tools described until now to block or enhance exosome secretion have not been well evaluated for their possible effect on secretion of other EVs. Still valid but has evolved with increasing knowledge of the existence of different EV types. 1. 21 though having a greater percentage in incentivizing and promoting its personnel in different activities, and in levels of communication between workers and hierarchies. "A4 (V2) Raketenfertigung in Friedrichshafen 19421945", "V-2: Nazi Rocket Details Are Finally Revealed", Journal of the American Statistical Association, "A Rocket a Day Keeps the High Costs Away", "V2Rocket.com "Antwerp, The City of Sudden Death", "Air Raid Precautions Deaths and injuries", "Flying Bombs and Rockets, V2 Woolworths New Cross", "V-2s on Remagen; Attacks on the Ludendorff Bridge", "65th anniversary of the V2 rocket landing in Orpington", "Britain and Ballistic Missile Defence, 19422002", "V2ROCKET.COM Den Haag (The Hague, Wassenaar, Hoek van Holland (Hook of Holland)", "The 8th of September 1944 AD, First German V2 rocket lands on London", "This Week in EUCOM History: February 612, 1959", "Hitler's Rocket U-boat Program history of WW2 rocket submarine", "How a Nazi rocket could have put a Briton in space", "Helmut Groettrup the captured Russian who was Russian POW rocket scientist", Australia's Nazi rockets: How German V-2 flying bombs made their way Down Under, "Geek Pilgrimage: V2 rocket engine - Deutsches Technikmuseum Berlin", "Reinhold Krger (18.02.1930 - 29.05.2005)", "V2 (VERGELTUNGS-WAFFE 2) ROCKET (SECTIONED)", "More pictures of V2 recovery operation at Harwich", "V-2 Rocket on Display at the White Sands Missile Range Museum", History of Peenemnde and the discovery of the German missile development by the Allies, Reconstruction, restoration & refurbishment of a V-2 rocket, Hermann Ludewig Collection, The University of Alabama in Huntsville Archives and Special Collections, https://en.wikipedia.org/w/index.php?title=V-2_rocket&oldid=1121031924, Peenemnde Army Research Center and Airfield, Weapons and ammunition introduced in 1944, Short description is different from Wikidata, Wikipedia articles needing page number citations from October 2020, Articles with unsourced statements from March 2013, Articles with unsourced statements from June 2022, Articles with unsourced statements from July 2016, Wikipedia articles needing page number citations from June 2022, Articles needing additional references from September 2016, All articles needing additional references, Articles with failed verification from May 2020, Articles with dead external links from October 2022, Articles with permanently dead external links, Creative Commons Attribution-ShareAlike License 3.0, 88km (55mi) maximum altitude on long-range trajectory, 206km (128mi) maximum altitude if launched vertically. Deepest suite of quality products, highest client satisfaction, and strong market share contributed to its top ranking. Ursula is the fourth recipient of the award. A few studies have also proposed ways of modulating secretion of plasma membrane-derived EVs in mammals: the ARRDC1 protein uses the ESCRT machinery to induce budding of small EVs at the PM, and its blocking or depletion inhibits secretion of such EVs [300,301]. [16]:285 the first landed at Staveley Road, Chiswick, killing 63-year-old Mrs. Ada Harrison, three-year-old Rosemary Clarke, and Sapper Bernard Browning on leave from the Royal Engineers,[17]:11 and one that hit Epping with no casualties. [32]:7678, At launch the A-4 propelled itself for up to 65 seconds on its own power, and a program motor held the inclination at the specified angle until engine shutdown, after which the rocket continued on a ballistic free-fall trajectory. Aerocity Escorts @9831443300 provides the best Escort Service in Aerocity. Of note, some presumed contaminants may co-isolate with EVs and may even contribute to EV function. Von Braun, his brother Magnus von Braun, and seven others decided to surrender to the United States military (Operation Paperclip) to ensure they were not captured by the advancing Soviets or shot dead by the Nazis to prevent their capture. BASIC : Beginners All-purpose Symbolic Instruction Code; BCEAC : Banque centrale des tats d'Afrique centrale; BCEAO : Banque centrale des tats de lAfrique de lOuest; BCPST : Biologie Physique Chimie Science de la Terre; BICRA : Banking Industry Country Risk Assessment; BNSPR : Banque Nationale des Sangs de Phnotype Rare; BOAMP : Bulletin officiel des annonces de Xerox Greece was listed as the No. Xerox was awarded in the category of Integrated Campaign for its healthcare thought leadership campaign. Companies are ranked by their 2017 B2B e-commerce Web sales only. Donation BTC: bc1qqkpvmmpapdmt6va8unc6eps9w522ankpctrg7u We have updated the database! BestB2B Website: Ready for Real Business Positions of the German launch units changed a number of times. By 1939, eighteen injection heads in two concentric circles at the head of the 3mm (0.12-inch) thick sheet-steel chamber, were used to make the 25 ton motor. This tactic worked; more than half of the V-2s aimed at London landed outside the London Civil Defence Region. Xerox has a loyal following of printer and copier VARs, but is hoping to expand that base to networking and managed service providers. Jebsen Brain Tumor Research Centre, Department of Biomedicine, University of Bergen, Bergen, Norway, Utrecht University, University Medical Center Utrecht, Department of Neurosurgery, Brain Center Rudolf Magnus, Institute of Neurosciences, Utrecht, The Netherlands; Utrecht University, University Medical Center Utrecht, Department of Pathology, Utrecht, The Netherlands, Universitat de Valncia, Departament de Farmcia i Tecnologia Farmacutica i Parasitologia, rea de Parasitologia, Valencia, Spain; Universitat de Valncia, Health Research Institute La Fe, Joint Research Unit on Endocrinology, Nutrition and Clinical Dietetics, Valencia, Spain, Universit degli Studi di Milano, Department of Clinical Sciences and Community Health, EPIGET LAB, Milan, Italy, A.C.Camargo Cancer Center, So Paulo, Brazil, University of Gothenburg, Sahlgrenska Academy, Department of Rheumatology and Inflammation Research, Gothenburg, Sweden, University of Southern California, Los Angeles, CA, USA, SickKids Hospital, Department of Anesthesia and Pain Medicine, Toronto, Canada; University of Toronto, Department of Anesthesia, Toronto, Canada, Florida State University College of Medicine, Department of Biomedical Sciences, Tallahassee, FL, USA, The School of Biomedical Sciences, University of Western Australia, Perth, Australia, University of Antwerp, Centre for Proteomics, Antwerp, Belgium; Vlaamse Instelling voor Technologisch Onderzoek (VITO), Mol, Belgium, Georg-Speyer-Haus Institute for Tumor Biology and Experimental Therapy, Frankfurt, Germany, QIMR Berghofer Medical Research Institute, Herston, Australia, Aalborg University Hospital, Department of Clinical Immunology, Aalborg, Denmark; EVSEARCH.DK, Denmark, Namur Thrombosis and Hemostasis Center (NTHC), NARILIS, Namur, Belgium; Universit Catholique de Louvain, CHU UCL Namur, Hematology-Hemostasis Laboratory, Yvoir, Belgium, University of Padova, Department of Womens and Childrens Health, Padova, Italy, The Johns Hopkins University School of Medicine, Department of Molecular and Comparative Pathobiology, Baltimore, MD, USA, Brown University, Women and Infants Hospital, Providence, RI, USA, German Cancer Consortium (DKTK), Partner Site Freiburg and German Cancer Research Center (DKFZ), Heidelberg, Germany; Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Institute for Infection Prevention and Hospital Epidemiology, Freiburg, Germany, Aarhus University, Department of Clinical Medicine, Aarhus, Denmark, Sorbonne Universit, Centre National de la Recherche Scientifique, Research Unit Biology of Adaptation and Aging (B2A), Team Compensation in Neurodegenerative and Aging (Brain-C), Paris, France, University of Pisa, Centro Dipartimentale di Biologia Cellulare Cardio-Respiratoria, Pisa, Italy, Universidade Federal do Rio de Janeiro, Instituto de Microbiologia, Rio de Janeiro, Brazil, National Institutes of Health, National Institute on Aging, Baltimore, MD, USA, University of Lige, GIGA-R(MBD), PSI Laboratory, Lige, Belgium, Queen Mary University of London, Blizard Institute, Epigenetics & Cellular Senescence Group, London, UK, National Cancer Center Research Institute, Division of Molecular and Cellular Medicine, Tokyo, Japan, McGill University, The Research Institute of the McGill University Health Centre, Montreal, Canada, IIS-Fundacion Jimenez Diaz-UAM, Department of Nephrology and Hypertension, Madrid, Spain; Spanish Kidney Research Network, REDINREN, Madrid, Spain; Universidad Autnoma de Madrid, School of Medicine, Department of Medicine, Madrid, Spain, Graduate School of Public Health at the University of Pittsburgh, Division of Occupational and Environmental Medicine, Pittsburgh, PA, USA, AstraZeneca, Discovery Sciences, IMED Biotech Unit, Cambridge, UK, Statens Serum Institut, Department of Autoimmunology and Biomarkers, Copenhagen, Denmark; University of Copenhagen, Faculty of Health and Medical Sciences, Novo Nordisk Foundation Center for Protein Research, Copenhagen, Denmark, University of Buenos Aires, Instituto de Investigaciones Biomdicas en Retrovirus y SIDA (INBIRS), Buenos Aires, Argentina, Amsterdam University Medical Centers, Department of Pathology, Amsterdam, The Netherlands, Spanish National Cancer Research Center (CNIO), Molecular Oncology Programme, Microenvironment and Metastasis Laboratory, Madrid, Spain, IRCCS - Istituto Ortopedico Rizzoli, Laboratory for Orthopaedic Pathophysiology and Regenerative Medicine, Bologna, Italy, The Scripps Research Institute-Scripps Florida, Department of Molecular Medicine, Jupiter, FL, USA, Radboud University Medical Center, Department of Rheumatology, Nijmegen, The Netherlands, Duke University Medical Center, Departments of Medicine and Immunology, Durham, NC, USA; Durham VAMC, Medical Research Service, Durham, NC, USA, Philipps University Marburg, Experimental Tumor Biology, Marburg, Germany, Pontificia Universidad Catlica de Chile, Advanced Center for Chronic Diseases (ACCDiS), Santiago, Chile; Pontificia Universidad Catlica de Chile, Faculty of Medicine, Department of Hematology-Oncology, Santiago, Chile, CNR Institute of Neuroscience, Milan, Italy, University of California, San Francisco, CA, USA; Veterans Affairs Medical Center, San Francisco, CA, USA, The Warren Alpert Medical School of Brown University, Department of Medicine, Providence, RI, USA, CSGI - Research Center for Colloids and Nanoscience, Florence, Italy; University of Brescia, Department of Molecular and Translational Medicine, Brescia, Italy, Department of Veterans Affairs, San Francisco, CA, USA; University of California, San Francisco, CA, USA, University of Palermo, Department of Biopathology and Medical Biotechnologies, Palermo, Italy, McGill University, Montreal, Canada; McGill University, The Research Institute of the McGill University Health Centre, Montreal, Canada, Instituto Oswaldo Cruz, Rio de Janeiro, Brazil; Universidade Federal de Paran, Paran, Brazil, Institut Curie, CNRS UMR144, PSL Research University, Paris, France, University of Michigan Medical School, Ann Arbor, MI, USA, Weizmann Institute of Science, Department of Biomolecular Sciences, Rehovot, Israel, University Medical Center Hamburg-Eppendorf, Department of Neurosurgery, Hamburg, Germany, University of Minnesota Medical School, Institute on the Biology of Aging and Metabolism, Department of Biochemistry, Molecular Biology and Biophysics, Minneapolis, MN, USA, CNC, Coimbra, Portugal; Exogenus Therapeutics, Cantanhede, Portugal, Paracelsus Medical University, Department of Transfusion Medicine, Salzburg, Austria; Paracelsus Medical University, GMP Unit, Salzburg, Austria; Spinal Cord Injury & Tissue Regeneration Center Salzburg (SCI-TReCS), Salzburg, Austria, University of Lyon, Lyon-Sud Faculty of Medicine, CarMeN Laboratory (UMR INSERM 1060-INRA 1397), Pierre-Bnite, France, Maastricht University, GROW, School for Oncology and Developmental Biology, Maastricht Radiation Oncology (MaastRO) Lab, Maastricht, The Netherlands, Sapienza University of Rome, Department of Experimental Medicine, Rome, Italy, West Virginia University, Morgantown, WV, USA, American Red Cross, Scientific Affairs, Gaithersburg, MD, USA, Icahn School of Medicine at Mount Sinai, Department of Medicine, Cardiology, New York City, NY, USA, Advanced Center for Chronic Diseases, Santiago, Chile; University of Chile, Faculty of Chemical and Pharmaceutical Science, Laboratory of Nanobiotechnology and Nanotoxicology, Santiago, Chile, Clnica las Condes, Extracellular Vesicles in Personalized Medicine Group, Santiago, Chile, Oregon Health & Science University, Department of Anesthesiology & Perioperative Medicine, Portland, OR, USA, Technische Universitt Darmstadt, Department of Biology, Darmstadt, Germany, University Medical Center Utrecht, Laboratory for Clinical Chemistry & Hematology, Utrecht, The Netherlands, University of Toronto, Department of Laboratory Medicine and Pathobiology, Toronto, Canada; University of Toronto, Department of Medicine, Division of Neurology, Toronto, Canada, University of California, Los Angeles, California NanoSystems Institute, Los Angeles, CA, USA; University of California, Los Angeles, Department of Pathology and Laboratory Medicine, Los Angeles, CA, USA; University of California, Los Angeles, Jonsson Comprehensive Cancer Center, Los Angeles, CA, USA, Royan Institute for Stem Cell Biology and Technology, ACECR, Cell Science Research Center, Department of Stem Cells and Developmental Biology, Tehran, Iran, University of Gothenburg, Institute of Clinical Sciences, Department of Surgery, Sahlgrenska Cancer Center, Gothenburg, Sweden; University of Gothenburg, Institute of Medicine at Sahlgrenska Academy, Krefting Research Centre, Gothenburg, Sweden, Research Service, Olin E. Teague Veterans Medical Center, Temple, TX, USA; Texas A&M University College of Medicine, Institute for Regenerative Medicine and Department of Molecular and Cellular Medicine, College Station, TX, USA, University of Helsinki, EV Core Facility, Helsinki, Finland; University of Helsinki, Faculty of Biological and Environmental Sciences, Molecular and Integrative Biosciences Research Programme, EV group, Helsinki, Finland, INEB - Instituto de Engenharia Biomdica, Porto, Portugal; University of Porto, i3S-Instituto de Investigao e Inovao em Sade, Porto, Portugal; University of Porto, ICBAS - Instituto de Cincias Biomdicas Abel Salazar, Porto, Portugal, Maria Sklodowska-Curie Institute - Oncology Center, Gliwice Branch, Gliwice, Poland, Kansas State University, College of Veterinary Medicine, Manhattan, KS, USA, Ren Rachou Institute/FIOCRUZ, Belo Horizonte, Brazil, QIMR Berghofer Medical Research Institute, Herston, Australia; The University of Queensland, Brisbane, Australia, Washington University, Saint Louis, MO, USA, Harvard Medical School, Department of Medicine, Boston, MA, USA; Massachusetts General Cancer Center, Boston, MA, USA, FAU Erlangen-Nuremberg, Transfusion and Haemostaseology Department, Erlangen, Germany, University of Auckland, Department of Molecular Medicine and Pathology, Auckland, New Zealand, Hiroshima University, Institute of Biomedical & Health Sciences, Department of Cellular and Molecular Biology, Hiroshima, Japan, University of Michigan, Biointerfaces Institute, Ann Arbor, MI, USA; University of Michigan, Department of Biomedical Engineering, Ann Arbor, MI, USA; University of Michigan, Department of Internal Medicine - Hematology/Oncology Division, Ann Arbor, MI, USA, Georgetown University, Department of Medicine, Washington, DC, USA; Sanjay Gandhi Postgraduate Institute of Medical Sciences, Department of Molecular Medicine & Biotechnology, Lucknow, India, National University of Singapore, Faculty of Dentistry, Singapore, INSERM U1068, Aix Marseille University, CNRS UMR7258, Marseille, France, UNIFESP, Departamento de Cincias Farmacuticas, Diadema, Brazil, Institut Pasteur de Montevideo, Functional Genomics Unit, Montevideo, Uruguay; Universidad de la Repblica, Faculty of Science, Nuclear Research Center, Analytical Biochemistry Unit, Montevideo, Uruguay, Beth Israel Deaconess Medical Center, Boston, MA, USA, University of Perugia, Department of Chemistry, Biology and Biotechnology, Perugia, Italy, University Medical Center Utrecht, Department of Nephrology and Hypertension, Utrecht, The Netherlands, TGen, Neurogenomics Division, Phoenix, AZ, USA, Center for Psychiatry and Neuroscience, INSERM U894, Paris, France, Department of Pathology, Erasmus MC, Erasmus Optical Imaging Centre, Rotterdam, The Netherlands, Mayo Clinic, Department of Orthopedic Surgery, Rochester, MN, USA, IPATIMUP, Institute of Molecular Pathology and Immunology of the University of Porto, Porto, Portugal; University of Porto, Faculty of Pharmacy (FFUP), Porto, Portugal; University of Porto, i3S-Instituto de Investigao e Inovao em Sade, Porto, Portugal, University of Kentucky, College of Medicine, Department of Physiology, Lexington, KY, USA, Universidade Federal do Rio Grande do Sul, Instituto de Cincias Bsicas da Sade, Departamento de Microbiologia, Imunologia e Parasitologia, Porto Alegre, Brazil, The Florey Institute of Neuroscience and Mental Health, Melbourne, Australia; The University of Melbourne, The Department of Medicine, Melbourne, Australia, UMR 7365 CNRS-Universit de Lorraine, Vanduvre-ls-Nancy, France, Oslo University Hospital Rikshospitalet, Research Institute of Internal Medicine, Oslo, Norway; Regional Research Network on Extracellular Vesicles, RRNEV, Oslo, Norway; University of Oslo, Institute of Clinical Medicine, Oslo, Norway, University of Gothenburg, The Sahlgrenska Academy, Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, Mlndal, Sweden, Case Western Reserve University, Department of Medicine, Cleveland, OH, USA; University Hospitals Cleveland Medical Center, Department of Medicine, Cleveland, OH, USA, Vanderbilt University School of Medicine, Department of Cell and Developmental Biology, Nashville, TN, USA, Danube University Krems, Department for Biomedical Research and Christian Doppler Laboratory for Innovative Therapy Approaches in Sepsis, Krems an der Donau, Austria, University of Wrzburg, Rudolf Virchow Center, Wrzburg, Germany, The University of Vermont Medical Center, Department of Medicine, Burlington, VT, USA, University Hospital RWTH Aachen, Department of Thoracic and Cardiovascular Surgery, Aachen, Germany, Karolinska Institute, Department of Medicine and Center for Molecular Medicine, Respiratory Medicine Unit, Stockholm, Sweden, Chinese Academy of Sciences, Wenzhou Institute of Biomaterials and Engineering, Wenzhou, China; Houston Methodist Research Institute, Department of Nanomedicine, Houston, TX, USA; Mayo Clinic, Department of Transplantation Medicine/Department of Physiology and Biomedical Engineering, Jacksonville, FL, USA, George Papanicolaou Hospital, Public Cord Blood Bank, Department of Haematology - BMT Unit, Thessaloniki, Greece, Universidade Federal de So Paulo Campus Diadema, Departamento de Cincias Farmacuticas, Laboratrio de Imunologia Celular e Bioqumica de Fungos e Protozorios, So Paulo, Brazil, Xiamen University, Department of Chemical Biology, Xiamen, China, Centro de Biologa Molecular Severo Ochoa, Instituto de Investigacin Sanitaria la Princesa (IIS-IP), Madrid, Spain; Universidad Autnoma de Madrid, Departamento de Biologa Molecular, Madrid, Spain, Tsinghua University, School of Pharmaceutical Sciences, Beijing, China, Technical University Eindhoven, Faculty Biomedical Technology, Eindhoven, The Netherlands, University of Padova, Department of Comparative Biomedicine and Food Science, Padova, Italy, Institute of Physiology CAS, Department of Biomaterials and Tissue Engineering, BIOCEV, Vestec, Czech Republic; Institute of Physiology CAS, Department of Biomaterials and Tissue Engineering, Prague, Czech Republic; University of California, Los Angeles, Department of Bioengineering, Los Angeles, CA, USA, Vilnius University, Institute of Biomedical Sciences, Department of Physiology, Biochemistry, Microbiology and Laboratory Medicine, Vilnius, Lithuania, Guangzhou Medical University, School of Pharmaceutical Sciences & the Fifth Affiliated Hospital, Key Laboratory of Molecular Target & Clinical Pharmacology, Guangzhou, China, Nanfang Hospital, Southern Medical University, Department of Clinical Laboratory Medicine, Guangzhou, China, Karolinska Institute, Clinical Research Center, Unit for Molecular Cell and Gene Therapy Science, Stockholm, Sweden, Aix-Marseille Universit, Institut Paoli-Calmettes, INSERM U1068, CNRS UMR7258, Centre de Recherche en Cancrologie de Marseille, Marseille, France; KU Leuven (Leuven University), Department of Human Genetics, Leuven, Belgium, University of California, Davis, Department of Nutrition, Davis, CA, USA. 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